CABP1 anticorps (Internal Region)

N° du produit ABIN6260388

L’anticorps Lapin Polyclonal anti-CABP1 a été validé pour WB et ELISA. Il convient pour détecter CABP1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CABP1 anticorps (Internal Region) (ABIN6260388)

Antigène: CABP1 (Calcium Binding Protein 1 (CABP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CABP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CABP1 anticorps

Épitope: Internal Region

Specificité: CABP1 Antibody detects endogenous levels of total CABP1.

Homologie: Pig,Bovine,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CABP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CABP1

Antigène: CABP1 (Calcium Binding Protein 1 (CABP1))

Autre désignation: CABP1

Sujet:

Description: Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs)(PubMed:14570872). Inhibits agonist-induced intracellular calcium signaling (PubMed:15980432). Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (PubMed:11865310). Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function (PubMed:15140941). Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels (PubMed:15895247). Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity).

Gene: CABP1

Poids moléculaire: 40 kDa

ID gène: 9478

UniProt: Q9NZU7

Pathways: Synaptic Membrane, Negative Regulation of Transporter Activity