CaMK2 alpha/delta anticorps

N° du produit ABIN6260427

Détail du produit anti-CaMK2 alpha/delta anticorps

Antigène: CaMK2 alpha/delta

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CaMK2 alpha/delta est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificité: CaMK2 alpha/delta Antibody detects endogenous levels of total CaMK2 alpha/delta

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CaMK2 alpha/delta

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Références pour anticorps anti-CaMK2 alpha/delta (ABIN6260427)

Cao, Xiao, Wang, Weng, Ding, Zhu, Lu: "Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." dans: Neurochemical research, (2018) (PubMed).

Détails sur CaMK2 alpha/delta

Antigène: CaMK2 alpha/delta

Abstract: CaMK2 alpha/delta Produits

Sujet:

Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

Gene: CAMK2A

Poids moléculaire: 50kDa

ID gène: 815

UniProt: Q9UQM7, Q13557