Caspase 4 anticorps
Aperçu rapide pour Caspase 4 anticorps (ABIN6260486)
Antigène
Voir toutes Caspase 4 (CASP4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Caspase-11 Antibody detects endogenous levels of total caspase-11
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Réactivité croisée
- Humain, Souris, Rat (Rattus)
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human caspase-11
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Isotype
- IgG
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Indications d'application
- WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
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Date de péremption
- 12 months
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- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
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Autre désignation
- caspase-11
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Sujet
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Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
Gene: CASP7
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Poids moléculaire
- 43 kDa
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ID gène
- 840
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UniProt
- P55210
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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