CBX5 anticorps (Internal Region)

N° du produit ABIN6260520

L’anticorps Lapin Polyclonal anti-CBX5 a été validé pour WB, ELISA, IHC, IF et ICC. Il convient pour détecter CBX5 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CBX5 anticorps (Internal Region) (ABIN6260520)

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-CBX5 anticorps

Épitope: Internal Region

Specificité: HP1 alpha Antibody detects endogenous levels of total HP1 alpha.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HP1 alpha, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CBX5

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Autre désignation: CBX5

Sujet:

Description: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Gene: CBX5

Poids moléculaire: 22kDa

ID gène: 23468

UniProt: P45973