CCL19 anticorps (N-Term)

N° du produit ABIN6260539

Détail du produit anti-CCL19 anticorps

Antigène: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL19 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: CCL19 Antibody detects endogenous levels of total CCL19.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CCL19, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CCL19

Antigène: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Autre désignation: CCL19 (CCL19 Produits)

Synonymes: anticorps CKb11, anticorps ELC, anticorps MIP-3b, anticorps MIP3B, anticorps SCYA19, anticorps CCL19, anticorps Scya19, anticorps exodus-3, anticorps C-C motif chemokine ligand 19, anticorps chemokine (C-C motif) ligand 19, anticorps CCL19, anticorps ccl19, anticorps Ccl19

Sujet:

Description: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Gene: CCL19

Poids moléculaire: 11kDa

ID gène: 6363

UniProt: Q99731

Pathways: Positive Regulation of Immune Effector Process