CD226 anticorps

N° du produit ABIN6260593

Cet anticorps anti-CD226 Polyclonal Lapin (ABIN6260593) détecte spécifiquement CD226 dans WB, ELISA, IF et ICC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD226 anticorps (ABIN6260593)

Antigène: CD226

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD226 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-CD226 anticorps

Specificité: CD226/DNAM-1 antibody detects endogenous levels of total CD226/DNAM-1

Réactivité croisée: Humain, Souris

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CD226/DNAM-1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:3000 IF/ICC: 1:100~1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur CD226

Antigène: CD226

Autre désignation: CD226/DNAM-1

Sujet:

Description: Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).

Gene: CD226

Poids moléculaire: 38kDa

ID gène: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints