CD300a anticorps (Internal Region)
Aperçu rapide pour CD300a anticorps (Internal Region) (ABIN6260608)
Antigène
Voir toutes CD300a (CD300A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- CD300A Antibody detects endogenous levels of total CD300A.
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human CD300A, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- CD300a (CD300A)
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Autre désignation
- CD300A
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Sujet
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Description: Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:10746781, PubMed:16339535, PubMed:9701027). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed:22043923).
Gene: CD300A
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Poids moléculaire
- 60 kDa
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ID gène
- 11314
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UniProt
- Q9UGN4
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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