CNGA3 anticorps (N-Term)

N° du produit ABIN6260908

Détail du produit anti-CNGA3 anticorps

Antigène: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNGA3 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: CNGA3 Antibody detects endogenous levels of total CNGA3.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CNGA3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CNGA3

Antigène: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Autre désignation: CNGA3 (CNGA3 Produits)

Synonymes: anticorps ACHM2, anticorps CCNC1, anticorps CCNCa, anticorps CCNCalpha, anticorps CNCG3, anticorps CNG3, anticorps CNGA3, anticorps cyclic nucleotide gated channel alpha 3, anticorps CNGA3, anticorps Cnga3

Sujet:

Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

Gene: CNGA3

Poids moléculaire: 79 kDa

ID gène: 1261

UniProt: Q16281

Pathways: Phototransduction