COLEC12 anticorps (C-Term)

N° du produit ABIN6260935

Cet anticorps anti-COLEC12 est un anticorps Lapin Polyclonal détectant COLEC12 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour COLEC12 anticorps (C-Term) (ABIN6260935)

Antigène: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COLEC12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-COLEC12 anticorps

Épitope: C-Term

Specificité: COLEC12 Antibody detects endogenous levels of total COLEC12.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human COLEC12, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur COLEC12

Antigène: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Autre désignation: COLEC12

Sujet:

Description: Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease.

Gene: COLEC12

Poids moléculaire: 82 kDa

ID gène: 81035

UniProt: Q5KU26

Pathways: Activation of Innate immune Response