COX1 anticorps (C-Term)

N° du produit ABIN6260980

Cet anticorps anti-COX1 Polyclonal Lapin (ABIN6260980) détecte spécifiquement COX1 dans WB, IHC, IF et ICC. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour COX1 anticorps (C-Term) (ABIN6260980)

Antigène: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-COX1 anticorps

Épitope: C-Term

Fonction: Cox1 Antibody

Specificité: Cox1 Antibody detects endogenous levels of total Cox1.

Homologie: Pig,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Cox1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur COX1

Antigène: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Autre désignation: Cox1

Sujet:

Description: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Gene: PTGS1

Poids moléculaire: 70kDa

ID gène: 5742

UniProt: P23219

Pathways: Proton Transport