Complexin 1 anticorps (N-Term)

N° du produit ABIN6261003

L’anticorps Lapin Polyclonal anti-Complexin 1 a été validé pour WB et IHC. Il convient pour détecter Complexin 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Complexin 1 anticorps (N-Term) (ABIN6261003)

Antigène: Complexin 1 (CPLX1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complexin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Complexin 1 anticorps

Épitope: N-Term

Specificité: CPLX1 Antibody detects endogenous levels of total CPLX1.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CPLX1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Complexin 1

Antigène: Complexin 1 (CPLX1)

Autre désignation: CPLX1

Sujet:

Description: Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:21785414). Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse (PubMed:21785414). Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

Gene: CPLX1

Poids moléculaire: 15-20 kDa

ID gène: 10815

UniProt: O14810

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport