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DKK3 anticorps

Reactivité: Humain, Souris, Rat WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261307
  • Antigène Voir toutes DKK3 Anticorps
    DKK3
    Reactivité
    • 56
    • 35
    • 17
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 68
    • 5
    • 2
    • 1
    Lapin
    Clonalité
    • 69
    • 7
    Polyclonal
    Conjugué
    • 35
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DKK3 est non-conjugé
    Application
    • 57
    • 38
    • 29
    • 13
    • 13
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    DKK3 Antibody detects endogenous levels of total DKK3
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human DKK3
    Isotype
    IgG
    Top Product
    Discover our top product DKK3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    DKK3
    Abstract
    DKK3 Produits
    Synonymes
    anticorps REIC, anticorps RIG, anticorps reic, anticorps dkk-3, anticorps AW061014, anticorps C87148, anticorps Reic, anticorps p29, anticorps dickkopf WNT signaling pathway inhibitor 3, anticorps dickkopf WNT signaling pathway inhibitor 3 S homeolog, anticorps DKK3, anticorps dkk3, anticorps dkk3.S, anticorps Dkk3
    Sujet

    Description: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

    Gene: DKK3

    Poids moléculaire
    38kDa
    ID gène
    27122
    UniProt
    Q9UBP4
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