DLC1 anticorps (N-Term)

N° du produit ABIN6261308

Détail du produit anti-DLC1 anticorps

Antigène: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLC1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: DLC1 Antibody detects endogenous levels of total DLC1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DLC1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DLC1

Antigène: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Autre désignation: DLC1 (DLC1 Produits)

Synonymes: anticorps ARHGAP7, anticorps HP, anticorps STARD12, anticorps p122-RhoGAP, anticorps rhogap7, anticorps DLC-1, anticorps StARD12, anticorps Dlc-1, anticorps A730069N07Rik, anticorps Arhgap7, anticorps dlc-1, anticorps RhoGAP, anticorps Dlc1, anticorps DLC1 Rho GTPase activating protein, anticorps DLC1 Rho GTPase activating protein S homeolog, anticorps rho GTPase-activating protein 7, anticorps deleted in liver cancer 1, anticorps DLC1, anticorps dlc1.S, anticorps dlc1, anticorps LOC100456847, anticorps Dlc1, anticorps LOC100729904

Sujet:

Description: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Gene: DLC1

Poids moléculaire: 171kDa

ID gène: 10395

UniProt: Q96QB1

Pathways: Tube Formation, Positive Regulation of Endopeptidase Activity