DOM3Z anticorps (Internal Region)

N° du produit ABIN6261355

Détail du produit anti-DOM3Z anticorps

Antigène: DOM3Z (Dom-3 Homolog Z (DOM3Z))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOM3Z est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: DOM3Z Antibody detects endogenous levels of total DOM3Z.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DOM3Z, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DOM3Z

Antigène: DOM3Z (Dom-3 Homolog Z (DOM3Z))

Autre désignation: DXO (DOM3Z Produits)

Synonymes: anticorps ng6, anticorps dom3l, anticorps DXO, anticorps DOM3L, anticorps NG6, anticorps RAI1, anticorps decapping exoribonuclease, anticorps dom-3 homolog Z (C. elegans), anticorps decapping exoribonuclease L homeolog, anticorps DXO, anticorps DOM3Z, anticorps dxo, anticorps dxo.L, anticorps Dxo

Sujet:

Description: Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity).

Gene: DXO

Poids moléculaire: 45 kDa

ID gène: 1797

UniProt: O77932