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DPP4 anticorps (C-Term)

DPP4 Reactivité: Humain, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261360
  • Antigène Voir toutes DPP4 Anticorps
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    Épitope
    • 16
    • 14
    • 9
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 137
    • 44
    • 43
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 92
    • 66
    • 17
    • 3
    • 1
    Lapin
    Clonalité
    • 89
    • 88
    Polyclonal
    Conjugué
    • 80
    • 24
    • 19
    • 16
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DPP4 est non-conjugé
    Application
    • 78
    • 73
    • 50
    • 36
    • 33
    • 30
    • 22
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    CD26 Antibody detects endogenous levels of total CD26.
    Homologie
    Pig,Bovine,Horse,Rabbit
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CD26, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product DPP4 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    Autre désignation
    DPP4 (DPP4 Produits)
    Synonymes
    anticorps ADABP, anticorps ADCP2, anticorps CD26, anticorps DPPIV, anticorps TP103, anticorps MGC81966, anticorps MOP9.8, anticorps MOP9_8, anticorps DPP4, anticorps si:ch73-2d23.3, anticorps Cd26, anticorps Dpp-4, anticorps THAM, anticorps dipeptidyl peptidase 4, anticorps dipeptidyl-peptidase 4 S homeolog, anticorps prolyl oligopeptidase family protein, anticorps dipeptidyl-peptidase 4, anticorps dipeptidylpeptidase 4, anticorps DPP4, anticorps dpp4.S, anticorps AT5G24260, anticorps dpp4, anticorps Dpp4
    Sujet

    Description: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

    Gene: DPP4

    Poids moléculaire
    55-60 kDa
    ID gène
    1803
    UniProt
    P27487
    Pathways
    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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