EXT1 anticorps
Aperçu rapide pour EXT1 anticorps (ABIN6261628)
Antigène
Voir toutes EXT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- EXT1 Antibody detects endogenous levels of total EXT1
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Réactivité croisée
- Humain, Souris, Rat (Rattus)
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human EXT1
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
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Date de péremption
- 12 months
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- EXT1 (Exostosin 1 (EXT1))
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Autre désignation
- EXT1
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Sujet
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Description: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).
Gene: EXT1
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Poids moléculaire
- 86kDa
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ID gène
- 2131
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UniProt
- Q16394
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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