GDF11 anticorps (Internal Region)

N° du produit ABIN6261926

Cet anticorps Lapin Polyclonal détecte spécifiquement GDF11 dans WB, ELISA, ICC et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour GDF11 anticorps (Internal Region) (ABIN6261926)

Antigène: GDF11 (Growth Differentiation Factor 11 (GDF11))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-GDF11 anticorps

Épitope: Internal Region

Specificité: GDF11 Antibody detects endogenous levels of total GDF11.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GDF11, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GDF11

Antigène: GDF11 (Growth Differentiation Factor 11 (GDF11))

Autre désignation: GDF11

Sujet:

Description: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634).

Gene: GDF11

Poids moléculaire: 45 kDa

ID gène: 10220

UniProt: O95390