ARHGEF25/GEFT anticorps (Internal Region)

N° du produit ABIN6261936

Détail du produit anti-ARHGEF25/GEFT anticorps

Antigène: ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

Épitope: Internal Region

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF25/GEFT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: GEFT Antibody detects endogenous levels of total GEFT.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GEFT, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARHGEF25/GEFT

Antigène: ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

Autre désignation: ARHGEF25 (ARHGEF25 Produits)

Synonymes: anticorps GEFT, anticorps p63RhoGEF, anticorps 2410008H17Rik, anticorps D10Ertd610e, anticorps Geft, anticorps Rho guanine nucleotide exchange factor 25, anticorps Rho guanine nucleotide exchange factor (GEF) 25, anticorps ARHGEF25, anticorps Arhgef25

Sujet:

Description: May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis (By similarity).

Gene: ARHGEF25

Poids moléculaire: 64 kDa

ID gène: 115557

UniProt: Q86VW2