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GGT1 anticorps (N-Term)

GGT1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261947
  • Antigène Voir toutes GGT1 Anticorps
    GGT1 (gamma Glutamyltransferase 1 (GGT1))
    Épitope
    • 16
    • 14
    • 13
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 75
    • 38
    • 17
    • 6
    Humain, Souris, Rat
    Hôte
    • 75
    • 13
    • 1
    Lapin
    Clonalité
    • 78
    • 11
    Polyclonal
    Conjugué
    • 36
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GGT1 est non-conjugé
    Application
    • 72
    • 39
    • 23
    • 13
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    GGT1 Antibody detects endogenous levels of total GGT1.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human GGT1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GGT1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    GGT1 (gamma Glutamyltransferase 1 (GGT1))
    Autre désignation
    GGT1 (GGT1 Produits)
    Synonymes
    anticorps ggt1, anticorps zgc:64172, anticorps CD224, anticorps D22S672, anticorps D22S732, anticorps GGT, anticorps GGT 1, anticorps GTG, anticorps GGT-1, anticorps Ggtp, anticorps dwg, anticorps GGLUT, anticorps Ggt, anticorps GGT2, anticorps cd224, anticorps ggt, anticorps gtg, anticorps GGT1, anticorps ggt1-a, anticorps gamma-glutamyltransferase 1a, anticorps gamma-glutamyltransferase 1, anticorps gamma-glutamyltranspeptidase 1, anticorps gamma-glutamyltransferase 1 L homeolog, anticorps gamma-glutamyltransferase, anticorps gamma-glutamyltranspeptidase Ggt1, anticorps ggt1a, anticorps GGT1, anticorps Ggt1, anticorps ggt1, anticorps LOC470168, anticorps ggt1.L, anticorps ggt, anticorps Bcep18194_A6223, anticorps h16_A1098, anticorps Shewana3_2487, anticorps Bcep1808_2978
    Sujet

    Description: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.

    Gene: GGT1

    Poids moléculaire
    60kDa
    ID gène
    2678
    UniProt
    P19440
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