GRIA4 anticorps

N° du produit ABIN6262083

Détail du produit anti-GRIA4 anticorps

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: GRIA4 Antibody detects endogenous levels of total GRIA4

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GRIA4

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur GRIA4

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Autre désignation: GRIA4 (GRIA4 Produits)

Synonymes: anticorps GLUR4, anticorps GLUR4C, anticorps GLURD, anticorps GluA4, anticorps GluR4, anticorps GluR4d, anticorps GLUR4/D, anticorps glur4, anticorps GluR-D, anticorps Glur-4, anticorps Glur4, anticorps Gluralpha4, anticorps spkw1, anticorps DKFZp459P0616, anticorps glur4a, anticorps gria4, anticorps iGluR4, anticorps ZfGluR4b, anticorps fj46g06, anticorps glur4b, anticorps wu:fj46g06, anticorps glutamate ionotropic receptor AMPA type subunit 4, anticorps glutamate receptor, ionotropic, AMPA 4, anticorps glutamate receptor, ionotropic, AMPA4 (alpha 4), anticorps glutamate receptor, ionotropic, AMPA 4a, anticorps glutamate receptor, ionotropic, AMPA 4b, anticorps GRIA4, anticorps gria4, anticorps Gria4, anticorps gria4a, anticorps gria4b

Sujet:

Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gene: GRIA4

Poids moléculaire: 120 kDa

ID gène: 2893

UniProt: P48058

Pathways: Signalisation PI3K-Akt