HSPH1 anticorps (C-Term)
Aperçu rapide pour HSPH1 anticorps (C-Term) (ABIN6262390)
Antigène
Voir toutes HSPH1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- HSP105 Antibody detects endogenous levels of total HSP105.
-
Homologie
- Horse,Rabbit,Dog
-
Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogène
- A synthesized peptide derived from human HSP105, corresponding to a region within C-terminal amino acids.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Date de péremption
- 12 months
-
-
- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
-
Autre désignation
- HSPH1
-
Sujet
-
Description: Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed:24318877). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).
Gene: HSPH1
-
Poids moléculaire
- 97 kDa
-
ID gène
- 10808
-
UniProt
- Q92598
Antigène
-