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Id2 anticorps (C-Term)

Id2 Reactivité: Humain, Rat, Souris ELISA, IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262442
  • Antigène Voir toutes Id2 Anticorps
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Épitope
    • 15
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 30
    • 30
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 40
    • 5
    • 1
    Lapin
    Clonalité
    • 42
    • 4
    Polyclonal
    Conjugué
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Id2 est non-conjugé
    Application
    • 19
    • 17
    • 13
    • 13
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Specificité
    ID2 Antibody detects endogenous levels of total ID2.
    Homologie
    Pig,Bovine,Horse,Sheep,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human ID2, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product Id2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Autre désignation
    ID2 (Id2 Produits)
    Synonymes
    anticorps AI255428, anticorps C78922, anticorps Idb2, anticorps bHLHb26, anticorps Ac2-300, anticorps GIG8, anticorps ID2A, anticorps ID2H, anticorps XId2, anticorps id2-A, anticorps inhibitor of DNA binding 2, anticorps inhibitor of DNA binding 2, HLH protein, anticorps inhibitor of DNA binding 2 L homeolog, anticorps Id2, anticorps ID2, anticorps id2.L
    Sujet

    Description: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

    Gene: ID2

    Poids moléculaire
    18kDa
    ID gène
    3398
    UniProt
    Q02363
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