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Interleukin 17a anticorps (Internal Region)

Cet anticorps anti-Interleukin 17a est un anticorps Lapin Polyclonal détectant Interleukin 17a dans ELISA, WB, IHC, IF et ICC. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 3+ publications.
N° du produit ABIN6262537

Aperçu rapide pour Interleukin 17a anticorps (Internal Region) (ABIN6262537)

Antigène

Voir toutes Interleukin 17a (IL17A) Anticorps
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivité

  • 94
  • 59
  • 17
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
Humain, Souris, Rat

Hôte

  • 60
  • 52
  • 29
  • 6
  • 2
  • 2
Lapin

Clonalité

  • 84
  • 66
  • 1
Polyclonal

Conjugué

  • 73
  • 22
  • 14
  • 9
  • 9
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Interleukin 17a est non-conjugé

Application

  • 72
  • 54
  • 48
  • 19
  • 16
  • 11
  • 11
  • 10
  • 9
  • 7
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Épitope

    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    Specificité

    IL17A Antibody detects endogenous levels of total IL17A.

    Homologie

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogène

    A synthesized peptide derived from human IL17A, corresponding to a region within the internal amino acids.

    Isotype

    IgG
  • Indications d'application

    WB 1:200-1:1500, IHC 1:50-1:200, IF/ICC 1:20-1:50, ELISA(peptide) 1:20000-1:40000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C. Stable for 12 months from date of receipt.

    Date de péremption

    12 months
  • Zhong, Gao, Zhou, Lin, Chen, Huang, Huang, Zhou, Huang, Nie, Liu, Chen, Zhou, Lv: "Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation." dans: Oncotarget, Vol. 8, Issue 25, pp. 40486-40500, (2018) (PubMed).

    Wang, Wei, Fan, Ding, Tian, Zhou, Cheng: "Progranulin Is Positively Associated with Intervertebral Disc Degeneration by Interaction with IL-10 and IL-17 Through TNF Pathways." dans: Inflammation, (2018) (PubMed).

    Yan, Yang, Han, Feng: "Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats." dans: Molecular medicine reports, Vol. 14, Issue 2, pp. 1601-9, (2016) (PubMed).

  • Antigène

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    Autre désignation

    IL17A

    Sujet

    Description: Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).

    Gene: IL17A

    Poids moléculaire

    18kDa

    ID gène

    3605

    UniProt

    Q16552
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