Interleukin 17a anticorps (Internal Region)
Aperçu rapide pour Interleukin 17a anticorps (Internal Region) (ABIN6262537)
Antigène
Voir toutes Interleukin 17a (IL17A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- IL17A Antibody detects endogenous levels of total IL17A.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human IL17A, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:200-1:1500, IHC 1:50-1:200, IF/ICC 1:20-1:50, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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: "Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation." dans: Oncotarget, Vol. 8, Issue 25, pp. 40486-40500, (2018) (PubMed).
: "Progranulin Is Positively Associated with Intervertebral Disc Degeneration by Interaction with IL-10 and IL-17 Through TNF Pathways." dans: Inflammation, (2018) (PubMed).
: "Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats." dans: Molecular medicine reports, Vol. 14, Issue 2, pp. 1601-9, (2016) (PubMed).
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: "Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation." dans: Oncotarget, Vol. 8, Issue 25, pp. 40486-40500, (2018) (PubMed).
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Autre désignation
- IL17A
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Sujet
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Description: Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
Gene: IL17A
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Poids moléculaire
- 18kDa
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ID gène
- 3605
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UniProt
- Q16552
Antigène
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