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KRT17 anticorps (C-Term)

KRT17 Reactivité: Humain, Rat, Souris WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262776
  • Antigène Voir toutes KRT17 Anticorps
    KRT17 (Keratin 17 (KRT17))
    Épitope
    • 15
    • 15
    • 12
    • 11
    • 10
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 123
    • 46
    • 28
    • 18
    • 13
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 99
    • 35
    Lapin
    Clonalité
    • 86
    • 48
    Polyclonal
    Conjugué
    • 56
    • 16
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KRT17 est non-conjugé
    Application
    • 102
    • 43
    • 37
    • 30
    • 27
    • 26
    • 22
    • 20
    • 18
    • 14
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
    Specificité
    Cytokeratin 17 Antibody detects endogenous levels of total Cytokeratin 17.
    Homologie
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Cytokeratin 17, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product KRT17 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    KRT17 (Keratin 17 (KRT17))
    Autre désignation
    KRT17 (KRT17 Produits)
    Synonymes
    anticorps K17, anticorps Krt1-17, anticorps PC, anticorps PC2, anticorps PCHC1, anticorps Ka17, anticorps KRT17, anticorps krt16, anticorps si:dkeyp-113d7.7, anticorps KRT14, anticorps keratin 17, anticorps keratin 17 L homeolog, anticorps keratin 17, type I, anticorps keratin, type I cytoskeletal 17, anticorps Krt17, anticorps KRT17, anticorps krt17, anticorps krt17.L, anticorps LOC100737113, anticorps LOC102177275
    Sujet

    Description: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

    Gene: KRT17

    Poids moléculaire
    48kDa
    ID gène
    3872
    UniProt
    Q04695
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