K-RAS anticorps (C-Term)

N° du produit ABIN6262871

Détail du produit anti-K-RAS anticorps

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp K-RAS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: KRAS Antibody detects endogenous levels of total KRAS.

Homologie: Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human KRAS, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur K-RAS

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Autre désignation: KRAS (KRAS Produits)

Synonymes: anticorps wu:fa04e08, anticorps wu:fc14b12, anticorps wu:fc23g10, anticorps wu:fj89d12, anticorps zgc:85725, anticorps Kras2, anticorps c-Ki-ras, anticorps p21, anticorps C-K-RAS, anticorps CFC2, anticorps K-RAS2A, anticorps K-RAS2B, anticorps K-RAS4A, anticorps K-RAS4B, anticorps KI-RAS, anticorps KRAS1, anticorps KRAS2, anticorps NS, anticorps NS3, anticorps RASK2, anticorps AI929937, anticorps K-ras, anticorps Ki-ras, anticorps Kras-2, anticorps p21B, anticorps ras, anticorps k-ras, anticorps kras, anticorps kras-a, anticorps kras-b, anticorps rask2, anticorps K-RAS, anticorps p21ras, anticorps KRAS proto-oncogene, GTPase, anticorps v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, anticorps Kirsten rat sarcoma viral oncogene homolog, anticorps semicolonial-7, anticorps Ras family protein, anticorps GTPase KRas, anticorps Kirsten rat sarcoma viral oncogene homolog S homeolog, anticorps KRAS, anticorps kras, anticorps Kras, anticorps smco-7, anticorps PGTG_03066, anticorps Tsp_02666, anticorps Tsp_01642, anticorps rask, anticorps kras.S

Classe de substances: Viral Protein

Sujet:

Description: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).

Gene: KRAS

Poids moléculaire: 21kDa

ID gène: 3845

UniProt: P01116