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LC3B anticorps (N-Term)

MAP1LC3B Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262925
  • Antigène Voir toutes LC3B (MAP1LC3B) Anticorps
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    Épitope
    • 23
    • 16
    • 14
    • 12
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 134
    • 50
    • 35
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 123
    • 14
    • 7
    Lapin
    Clonalité
    • 129
    • 16
    Polyclonal
    Conjugué
    • 76
    • 14
    • 13
    • 10
    • 10
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp LC3B est non-conjugé
    Application
    • 88
    • 56
    • 51
    • 27
    • 23
    • 14
    • 13
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    LC3A/B Antibody detects endogenous levels of total LC3A/B.
    Homologie
    Pig,Zebrafish,Bovine,Sheep,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human LC3B, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MAP1LC3B Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Tang, Cui, Luan, Ruan, Wang, Yang, Wang, Liu, Wang: "Human tissue kallikrein 1 ameliorates erectile function via modulation of macroautophagy in aged transgenic rats." dans: Andrology, (2018) (PubMed).

    Feng, Lu, He, Wang, Qi, Pi, Zhang: "Mycobacterium smegmatis Induces Neurite Outgrowth and Differentiation in an Autophagy-Independent Manner in PC12 and C17.2 Cells." dans: Frontiers in cellular and infection microbiology, Vol. 8, pp. 201, (2018) (PubMed).

    Shao, Yang, Xu, Zhu, Huang, Li, Wu, Yue, Xiong, Chen, Kuang, Fan, Zhu, Zeng: "Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells." dans: Stem cell research & therapy, Vol. 9, Issue 1, pp. 219, (2018) (PubMed).

    Wu, Zheng, Bai, Xia, Zhang, Guo: "HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma." dans: OncoTargets and therapy, Vol. 11, pp. 4501-4510, (2018) (PubMed).

  • Antigène
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    Autre désignation
    MAP1LC3A,MAP1LC3B (MAP1LC3B Produits)
    Synonymes
    anticorps ATG8F, anticorps LC3B, anticorps MAP1A/1BLC3, anticorps MAP1LC3B-a, anticorps Map1lc3, anticorps Mpl3, anticorps zbs559, anticorps 1010001C15Rik, anticorps Atg8, anticorps LC3b, anticorps zgc:56434, anticorps wu:fb60g11, anticorps map1lc3b, anticorps MGC76283, anticorps MAP1LC3B, anticorps microtubule associated protein 1 light chain 3 beta, anticorps microtubule-associated protein 1 light chain 3 beta, anticorps microtubule associated protein 1 light chain 3 beta L homeolog, anticorps MAP1LC3B, anticorps Map1lc3b, anticorps map1lc3b, anticorps map1lc3b.L
    Sujet

    Description: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

    Gene: MAP1LC3B

    Poids moléculaire
    14.16 kDa
    ID gène
    84557, 81631
    UniProt
    Q9H492, Q9GZQ8
    Pathways
    Autophagy
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