MAD1L1 anticorps (N-Term)

N° du produit ABIN6263047

Cet anticorps anti-MAD1L1 est un anticorps Lapin Polyclonal détectant MAD1L1 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MAD1L1 anticorps (N-Term) (ABIN6263047)

Antigène: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAD1L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MAD1L1 anticorps

Épitope: N-Term

Specificité: MAD1L1 Antibody detects endogenous levels of total MAD1L1.

Homologie: Pig,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MAD1L1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MAD1L1

Antigène: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Autre désignation: MAD1L1

Sujet:

Description: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.

Gene: MAD1L1

Poids moléculaire: 83kDa

ID gène: 8379

UniProt: Q9Y6D9

Pathways: M Phase