MECP2 anticorps (C-Term)
Aperçu rapide pour MECP2 anticorps (C-Term) (ABIN6263186)
Antigène
Voir toutes MECP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- MeCP2 Antibody detects endogenous levels of total MeCP2.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human MeCP2, corresponding to a region within C-terminal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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Autre désignation
- MECP2
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Sujet
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Description: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Gene: MECP2
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Poids moléculaire
- 75 kDa
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ID gène
- 4204
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UniProt
- P51608
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Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
Antigène
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