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MEMO1 anticorps (N-Term)

MEMO1 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6263219
  • Antigène Voir toutes MEMO1 Anticorps
    MEMO1 (Mediator of Cell Motility 1 (MEMO1))
    Épitope
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 21
    • 9
    • 9
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 19
    • 2
    Lapin
    Clonalité
    • 19
    • 2
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MEMO1 est non-conjugé
    Application
    • 11
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    MEMO1 Antibody detects endogenous levels of total MEMO1.
    Homologie
    Pig,Zebrafish,Bovine,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MEMO1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MEMO1 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    MEMO1 (Mediator of Cell Motility 1 (MEMO1))
    Autre désignation
    MEMO1 (MEMO1 Produits)
    Sujet

    Description: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

    Gene: MEMO1

    Poids moléculaire
    33 kDa
    ID gène
    51072
    UniProt
    Q9Y316
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