MX1 anticorps (C-Term)

N° du produit ABIN6263446

Détail du produit anti-MX1 anticorps

Antigène: MX1 (Myxovirus Resistance Protein 1 (MX1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: MX1 Antibody detects endogenous levels of total MX1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MX1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MX1

Antigène: MX1 (Myxovirus Resistance Protein 1 (MX1))

Autre désignation: MX1 (MX1 Produits)

Synonymes: anticorps IFI78, anticorps AI893580, anticorps Mx, anticorps Mx-1, anticorps IFI-78K, anticorps MX, anticorps MxA, anticorps Mx1-b, anticorps Mx1B, anticorps OGTPBP, anticorps ONBP, anticorps myxovirus (influenza virus) resistance 1, anticorps MX dynamin-like GTPase 1, anticorps MX dynamin like GTPase 1, anticorps Mx1, anticorps MX1

Sujet:

Description: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Gene: MX1

Poids moléculaire: 76kDa

ID gène: 4599

UniProt: P20591