NEUROD2 anticorps (Internal Region)

N° du produit ABIN6263551

Détail du produit anti-NEUROD2 anticorps

Antigène: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEUROD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: NDF2 Antibody detects endogenous levels of total NDF2.

Homologie: Pig,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NDF2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NEUROD2

Antigène: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Autre désignation: NEUROD2 (NEUROD2 Produits)

Synonymes: anticorps NEUROD2, anticorps ndrf, anticorps MGC145932, anticorps Ndrf, anticorps bHLHa1, anticorps ndr2, anticorps wu:fj49a11, anticorps zNdr2, anticorps NDRF, anticorps neuronal differentiation 2, anticorps neurogenic differentiation 2, anticorps NEUROD2, anticorps neurod2, anticorps Neurod2

Sujet:

Description: Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation, prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections, involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).

Gene: NEUROD2

Poids moléculaire: 48kDa

ID gène: 4761

UniProt: Q15784