Nkx2-2 anticorps (Internal Region)

N° du produit ABIN6263646

L’anticorps Lapin Polyclonal anti-Nkx2-2 a été validé pour IF, WB, ELISA et ICC. Il convient pour détecter Nkx2-2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Nkx2-2 anticorps (Internal Region) (ABIN6263646)

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nkx2-2 est non-conjugé

Application: Immunofluorescence (IF), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-Nkx2-2 anticorps

Épitope: Internal Region

Specificité: NKX22 Antibody detects endogenous levels of total NKX22.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NKX22, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Nkx2-2

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Autre désignation: NKX2-2

Sujet:

Description: Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity).

Gene: NKX2-2

Poids moléculaire: 30 kDa

ID gène: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis