OAZ3 anticorps (Internal Region)

N° du produit ABIN6263789

Détail du produit anti-OAZ3 anticorps

Antigène: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAZ3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: OAZ3 Antibody detects endogenous levels of total OAZ3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human OAZ3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur OAZ3

Antigène: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Autre désignation: OAZ3 (OAZ3 Produits)

Synonymes: anticorps Az3, anticorps Oaz-t, anticorps AZ3, anticorps OAZ-t, anticorps TISP15, anticorps Az-3, anticorps ornithine decarboxylase antizyme 3, anticorps OAZ3, anticorps Oaz3

Sujet:

Description: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells (By similarity).

Gene: OAZ3

Poids moléculaire: 27 kDa

ID gène: 51686

UniProt: Q9UMX2