OBFC2A anticorps (Internal Region)

N° du produit ABIN6263791

Détail du produit anti-OBFC2A anticorps

Antigène: OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OBFC2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: OBFC2A Antibody detects endogenous levels of total OBFC2A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human OBFC2A, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur OBFC2A

Antigène: OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))

Autre désignation: NABP1 (OBFC2A Produits)

Synonymes: anticorps OBFC2A, anticorps SOSS-B2, anticorps SSB2, anticorps 4930434H03Rik, anticorps 4930442A21Rik, anticorps 4930488J04Rik, anticorps 4933440J18Rik, anticorps 5830411E10Rik, anticorps AI852561, anticorps Nbp1, anticorps Obfc2a, anticorps Ssb2, anticorps RGD1306658, anticorps nucleic acid binding protein 1, anticorps NABP1, anticorps Nabp1

Sujet:

Description: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

Gene: NABP1

Poids moléculaire: 22 kDa

ID gène: 64859

UniProt: Q96AH0