PIK3R6 anticorps (C-Term)

N° du produit ABIN6264219

L’anticorps Lapin Polyclonal anti-PIK3R6 a été validé pour WB, ELISA, IF, IHC et ICC. Il convient pour détecter PIK3R6 dans des échantillons de Humain.

Aperçu rapide pour PIK3R6 anticorps (C-Term) (ABIN6264219)

Antigène: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3R6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-PIK3R6 anticorps

Épitope: C-Term

Specificité: PIK3R6 Antibody detects endogenous levels of total PIK3R6.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PIK3R6, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PIK3R6

Antigène: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Autre désignation: PIK3R6

Sujet:

Description: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.

Gene: PIK3R6

Poids moléculaire: 84 kDa

ID gène: 146850

UniProt: Q5UE93

Pathways: Signalisation PI3K-Akt, Inositol Metabolic Process