BPIFA1 anticorps (Internal Region)

N° du produit ABIN6264311

Détail du produit anti-BPIFA1 anticorps

Antigène: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Épitope: Internal Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BPIFA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: PLUNC Antibody detects endogenous levels of total PLUNC.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PLUNC, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur BPIFA1

Antigène: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Autre désignation: BPIFA1 (BPIFA1 Produits)

Synonymes: anticorps LUNX, anticorps NASG, anticorps PLUNC, anticorps SPLUNC1, anticorps SPURT, anticorps bA49G10.5, anticorps Plunc, anticorps BPI fold containing family A member 1, anticorps BPI fold containing family A, member 1, anticorps BPIFA1, anticorps Bpifa1

Sujet:

Description: Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression.

Gene: BPIFA1

Poids moléculaire: 27 kDa

ID gène: 51297

UniProt: Q9NP55