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POLR2D anticorps (N-Term)

POLR2D Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264344
  • Antigène Voir toutes POLR2D Anticorps
    POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
    Épitope
    • 8
    • 7
    • 6
    • 6
    • 6
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 31
    • 3
    Lapin
    Clonalité
    • 32
    • 2
    Polyclonal
    Conjugué
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLR2D est non-conjugé
    Application
    • 22
    • 20
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    POLR2D Antibody detects endogenous levels of total POLR2D.
    Homologie
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human POLR2D, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product POLR2D Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
    Autre désignation
    POLR2D (POLR2D Produits)
    Synonymes
    anticorps wu:fa95b11, anticorps zgc:110435, anticorps HSRBP4, anticorps HSRPB4, anticorps RBP4, anticorps RPB16, anticorps 2310002G05Rik, anticorps 2610028L19Rik, anticorps RNA polymerase II subunit D, anticorps DNA-directed RNA polymerase II 16 kDa polypeptide, anticorps polymerase (RNA) II (DNA directed) polypeptide D, anticorps Polr2d, anticorps CpipJ_CPIJ006734, anticorps UREG_01395, anticorps LOC100282338, anticorps polr2d, anticorps POLR2D
    Sujet

    Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).

    Gene: POLR2D

    Poids moléculaire
    16kDa
    ID gène
    5433
    UniProt
    O15514
    Pathways
    Regulatory RNA Pathways
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