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POLR3E anticorps (N-Term)

POLR3E Reactivité: Humain ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264350
  • Antigène Voir toutes POLR3E Anticorps
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    Épitope
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 21
    • 2
    Lapin
    Clonalité
    • 21
    • 2
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLR3E est non-conjugé
    Application
    • 9
    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificité
    POLR3E Antibody detects endogenous levels of total POLR3E.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human POLR3E, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product POLR3E Anticorps primaire
  • Indications d'application
    WB 1:1000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    Autre désignation
    POLR3E (POLR3E Produits)
    Synonymes
    anticorps RPC5, anticorps SIN, anticorps Sin, anticorps MGC78924, anticorps RGD1308086, anticorps wu:fb12d10, anticorps wu:fs42e03, anticorps zgc:55592, anticorps RNA polymerase III subunit E, anticorps polymerase (RNA) III (DNA directed) polypeptide E, anticorps polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog, anticorps polymerase (RNA) III (DNA directed) polypeptide E (80kD), anticorps DNA-directed RNA polymerase III subunit RPC5, anticorps POLR3E, anticorps Polr3e, anticorps polr3e.L, anticorps polr3e, anticorps LOC608689
    Sujet

    Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

    Gene: POLR3E

    Poids moléculaire
    80kDa
    ID gène
    55718
    UniProt
    Q9NVU0
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