Peroxiredoxin 6 anticorps (Internal Region)
Aperçu rapide pour Peroxiredoxin 6 anticorps (Internal Region) (ABIN6264413)
Antigène
Voir toutes Peroxiredoxin 6 (PRDX6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- Peroxiredoxin 6 Antibody detects endogenous levels of total Peroxiredoxin 6.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human Peroxiredoxin 6, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- Peroxiredoxin 6 (PRDX6)
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Autre désignation
- PRDX6
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Sujet
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Description: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH . Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.
Gene: PRDX6
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Poids moléculaire
- 25kDa
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ID gène
- 9588
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UniProt
- P30041
Antigène
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