Reelin anticorps (N-Term)

N° du produit ABIN6264693

Détail du produit anti-Reelin anticorps

Antigène: Reelin (RELN)

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Reelin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: RELN Antibody detects endogenous levels of total RELN.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RELN, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Reelin

Antigène: Reelin (RELN)

Autre désignation: RELN (RELN Produits)

Synonymes: anticorps LIS2, anticorps PRO1598, anticorps RL, anticorps reeler, anticorps rl, anticorps Reelen, anticorps Rl, anticorps reln, anticorps RELN, anticorps MGC172539, anticorps reelin, anticorps reelin L homeolog, anticorps RELN, anticorps Reln, anticorps reln, anticorps reln.L, anticorps LOC579060

Sujet:

Description: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).

Gene: RELN

Poids moléculaire: 388kDa

ID gène: 5649

UniProt: P78509

Pathways: Synaptic Membrane