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RIOK3 anticorps (Internal Region)

RIOK3 Reactivité: Humain, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6264759
  • Antigène Voir toutes RIOK3 Anticorps
    RIOK3 (RRIO Kinase 3 (RIOK3))
    Épitope
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 26
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 22
    • 4
    Lapin
    Clonalité
    • 24
    • 2
    Polyclonal
    Conjugué
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RIOK3 est non-conjugé
    Application
    • 19
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    RIOK3 Antibody detects endogenous levels of total RIOK3.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human RIOK3, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RIOK3 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    RIOK3 (RRIO Kinase 3 (RIOK3))
    Autre désignation
    RIOK3 (RIOK3 Produits)
    Synonymes
    anticorps SUDD, anticorps 1200013N13Rik, anticorps D18Ertd331e, anticorps E130306C24Rik, anticorps Sudd, anticorps RIO kinase 3, anticorps RIO kinase 3 L homeolog, anticorps RIOK3, anticorps Riok3, anticorps riok3.L
    Sujet

    Description: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMed:24807708). Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling (PubMed:25865883). Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway (PubMed:19557502). May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA (PubMed:22418843).

    Gene: RIOK3

    Poids moléculaire
    59 kDa
    ID gène
    8780
    UniProt
    O14730
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