RNF19A anticorps (N-Term)
Aperçu rapide pour RNF19A anticorps (N-Term) (ABIN6264786)
Antigène
Voir toutes RNF19A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- RNF19A Antibody detects endogenous levels of total RNF19A.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human RNF19A, corresponding to a region within N-terminal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- RNF19A (Ring Finger Protein 19A (RNF19A))
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Autre désignation
- RNF19A
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Sujet
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Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.
Gene: RNF19A
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Poids moléculaire
- 90 kDa
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ID gène
- 25897
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UniProt
- Q9NV58
Antigène
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