SIN3B anticorps (Internal Region)

N° du produit ABIN6265088

Cet anticorps Lapin Polyclonal détecte spécifiquement SIN3B dans WB, ELISA, IF, IHC et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SIN3B anticorps (Internal Region) (ABIN6265088)

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-SIN3B anticorps

Épitope: Internal Region

Specificité: Sin3B Antibody detects endogenous levels of total Sin3B.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Sin3B, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SIN3B

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Autre désignation: SIN3B

Sujet:

Description: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

Gene: SIN3B

Poids moléculaire: 130kDa

ID gène: 23309

UniProt: O75182