SMCR7L anticorps (Internal Region)

N° du produit ABIN6265187

Cet anticorps Lapin Polyclonal détecte spécifiquement SMCR7L dans WB, IF, IHC et ICC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SMCR7L anticorps (Internal Region) (ABIN6265187)

Antigène: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMCR7L est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-SMCR7L anticorps

Épitope: Internal Region

Fonction: SMCR7L/MID51 Antibody

Specificité: SMCR7L/MID51 Antibody detects endogenous levels of total SMCR7L/MID51.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SMCR7L/MID51, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: IF/ICC 1:100-1:500,WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SMCR7L

Antigène: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Autre désignation: SMCR7L/MID51

Sujet:

Description: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.

Gene: MIEF1

Poids moléculaire: 48-51 kDa

ID gène: 54471

UniProt: Q9NQG6