TPMT anticorps (N-Term)

N° du produit ABIN6265692

L’anticorps Lapin Polyclonal anti-TPMT a été validé pour WB, ELISA et IHC. Il convient pour détecter TPMT dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TPMT anticorps (N-Term) (ABIN6265692)

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPMT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TPMT anticorps

Épitope: N-Term

Specificité: TPMT Antibody detects endogenous levels of total TPMT.

Homologie: Bovine,Horse,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TPMT, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TPMT

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Autre désignation: TPMT

Sujet:

Description: Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.

Gene: TPMT

Poids moléculaire: 28kDa

ID gène: 7172

UniProt: P51580