TRAP1 anticorps (Internal Region)
Aperçu rapide pour TRAP1 anticorps (Internal Region) (ABIN6265714)
Antigène
Voir toutes TRAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- TRAP1 Antibody detects endogenous levels of total TRAP1.
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Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human TRAP1, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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Autre désignation
- TRAP1
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Sujet
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Description: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Gene: TRAP1
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Poids moléculaire
- 80kDa
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ID gène
- 10131
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UniProt
- Q12931
Antigène
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