TSG101 anticorps

N° du produit ABIN6265767

L’anticorps Lapin Polyclonal anti-TSG101 a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter TSG101 dans des échantillons de Humain et Singe.

Aperçu rapide pour TSG101 anticorps (ABIN6265767)

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-TSG101 anticorps

Specificité: TSG101 Antibody detects endogenous levels of total TSG101

Réactivité croisée: Humain, Singe

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TSG101

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101

Sujet:

Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426).

Gene: TSG101

Poids moléculaire: 45 kDa

ID gène: 7251

UniProt: Q99816