TSG101 anticorps

N° du produit ABIN6265767

Détail du produit anti-TSG101 anticorps

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TSG101 Antibody detects endogenous levels of total TSG101

Réactivité croisée: Humain, Singe

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TSG101

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101 (TSG101 Produits)

Synonymes: anticorps CG9712, anticorps DmTSG101, anticorps Dmel\\CG9712, anticorps ESCRT-I, anticorps Tsg101, anticorps burs, anticorps dTSg101, anticorps dTsg101, anticorps dVps23, anticorps ept, anticorps tsg101, anticorps vps23, anticorps TSG101, anticorps MGC76193, anticorps TSG10, anticorps VPS23, anticorps AI255943, anticorps CC2, anticorps Rw, anticorps zgc:86926, anticorps tumor susceptibility 101, anticorps Tumor susceptibility gene 101, anticorps Tumor Susceptibility Gene homolog, anticorps tumor susceptibility gene 101, anticorps tumor susceptibility 101a, anticorps tumor susceptibility 101 L homeolog, anticorps TSG101, anticorps tsg-101, anticorps tsg101, anticorps Tsg101, anticorps tsg101a, anticorps tsg101.L

Sujet:

Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426).

Gene: TSG101

Poids moléculaire: 45 kDa

ID gène: 7251

UniProt: Q99816