UFM1 anticorps (Internal Region)

N° du produit ABIN6265872

L’anticorps Lapin Polyclonal anti-UFM1 a été validé pour ELISA et WB. Il convient pour détecter UFM1 dans des échantillons de Humain et Souris.

Aperçu rapide pour UFM1 anticorps (Internal Region) (ABIN6265872)

Antigène: UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UFM1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-UFM1 anticorps

Épitope: Internal Region

Specificité: UFM1 Antibody detects endogenous levels of total UFM1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human UFM1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur UFM1

Antigène: UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

Autre désignation: UFM1

Sujet:

Description: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes (PubMed:15071506, PubMed:20018847). TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).

Gene: UFM1

Poids moléculaire: 9 kDa

ID gène: 51569

UniProt: P61960