USP6 anticorps (C-Term)

N° du produit ABIN6265934

Cet anticorps Lapin Polyclonal détecte spécifiquement USP6 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour USP6 anticorps (C-Term) (ABIN6265934)

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-USP6 anticorps

Épitope: C-Term

Fonction: USP6 Antibody

Specificité: USP6 Antibody detects endogenous levels of total USP6

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human USP6, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200,WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur USP6

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Autre désignation: USP6

Sujet:

Description: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Gene: USP6

Poids moléculaire: 159 kDa

ID gène: 9098

UniProt: P35125